A recent study indicates that people who stop using popular slimming jabs like Mounjaro or Wegovy tend to recover lost weight much more quickly than those who end conventional lifestyle plans.
Findings released in a prominent medical journal shows that while obese individuals frequently drop substantial amounts of their total mass while undergoing treatment, the mass comes back at an estimated rate of nearly a kilo each month once they quit.
"People buying such treatments need to be aware of the danger of rapid rebound weight gain when the therapy is stopped," cautioned expert Dr. Susan Jebb.
Such speed of recovery means a return to pre-treatment weight within about 18 months.
Comparing Therapies
The study, which looked at dozens of trials involving over 9,000 of patients, contrasted the effects of the injectable medications with older methods.
Researchers note that individuals who shed pounds through diet and exercise typically see a less rapid creep back—approximately 100 grams monthly—once they finish.
The Reason for the Quick Regain
Doctors suggest the mode of action of the injections explains the amplified rebound.
These medications mimic a natural hormone called glucagon-like peptide-1, which helps regulate appetite.
"Long-term administration of the hormone levels several times higher than the body's typical production could lead to the system to generate a reduced amount of its endogenous GLP-1, and may also reduce sensitivity to its effects," noted Dr. Adam Collins, a nutrition expert.
"Discontinuation of this medication means appetite is no longer kept in check, making overeating far more likely."
An Ongoing Issue?
Medical guidelines advise the jabs for individuals with obesity-related medical conditions, accompanied by prescribed diet and exercise modifications.
Professionals contend that, given the high risk of relapse, the therapy might need to be long-term.
This perspective is supported by drug manufacturers, who say that the results "emphasize the long-term character of excess weight," similar to managing diseases like hypertension.
User Accounts
Users who have discontinued the jabs explain a intense resurgence of hunger.
"I experienced a trigger activating and you're instantly ravenous," said a patient.
The struggle is worsened if patients have not developed permanent dietary or behavioural modifications during therapy.
Growing Adoption
Survey data show that millions of adults in the UK have used these injections in the last 12 months, with desire being substantial.
- Adoption is greater among females compared to men.
- The 40s and 50s demographic shows the highest level of interest.
- A large proportion obtain the medications through private healthcare rather than public health services.
In conclusion, experts stress that while the jabs are effective agents for weight loss, they are not a permanent fix and lasting health benefits hinges on ongoing behavioural changes.
